mRNA（阅读链接）

Posted 2022-12-16 幻灰龙

• Five things you need to know about: mRNA vaccine safety
• Five things you need to know about: mRNA vaccines
• Understanding mRNA COVID-19 Vaccines
• Why are mRNA vaccines so exciting?
  • While the concept seems simple, it required decades of work for mRNA vaccines to overcome a series of hurdles.
    • First, scientists learned how to modify mRNA so that it did not produce violent immune system reactions.
    • Second, they learned how to encourage immune system cells to gobble up the mRNA as it passed by in the blood.
    • Third, they learned how to coax those cells to make large amounts of the critical piece of protein.
    • Finally, they learned how to enclose the mRNA inside microscopically small capsules to protect it from being destroyed by chemicals in our blood.
  • Already, mRNA vaccines are being tested for other infectious agents, such as Ebola, Zika virus, and influenza. Cancer cells make proteins that also can be targeted by mRNA vaccines: indeed, recent progress was reported with melanoma. And theoretically, mRNA technology could produce proteins missing in certain diseases, like cystic fibrosis.
  • mRNA 这种技术一定会在未来彻底改变很多疾病的治疗。
• 一针辉瑞疫苗，其实是2万亿段代码：程序员逆向重建mRNA源代码
• Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine