vcf bed起始位置是0还是1

Posted 2023-03-09 qq_21478261

VCF

起始位置为1，

POS - position: The reference position, with the 1st base having position 1. Positions are sorted numerically, in increasing order, within each reference sequence CHROM. It is permitted to have multiple records with the same POS. Telomeres are indicated by using positions 0 or N+1, where N is the length of the corresponding chromosome or contig. (Integer, Required)

参考：https://samtools.github.io/hts-specs/VCFv4.2.pdf

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bed

起始位置为0，而且区间是左闭右开区间

the first three fields in each feature line are required:

1. chrom - name of the chromosome or scaffold. Any valid seq_region_name can be used, and ch